![]() ![]() Urea and creatinine concentrations in blood were measured and systemic vascular resistance was calculated. Blood samples were collected at induction of anesthesia, at the time of aortic clamping and declamping and 1 and 24 h following cessation of the bypass. 40 patients undergoing elective cardiac surgery with a high risk of either having chronically obstructive pulmonary disease or chronic renal failure were randomly included in the study to be perfused using pulsatile or continuous flows. Pulsatile roller pumps with a pulsatile control module and membrane oxygenator were used in a clinical setting. The effects of pulsatile perfusion on microcirculation and renal function in high-risk patients were evaluated in this study.
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